R-universe - healthinformaticsut (Health Informatics Lab, University of Tartu)

CohortContrast - Enrichment Analysis of Clinically Relevant Concepts in Common Data Model Cohort Data

Identifies clinically relevant concepts in Observational Medical Outcomes Partnership Common Data Model cohorts using an enrichment-based workflow. Defines target and control cohorts and extracts medical interventions that are over-represented in the target cohort during the observation period. Users can tune filtering and selection thresholds. The workflow includes chi-squared tests for two proportions with Yates continuity correction, logistic tests, and hierarchy and correlation mappings for relevant concepts. The results can be optionally explored using the bundled graphical user interface. For workflow details and examples, see <https://healthinformaticsut.github.io/CohortContrast/>.

Last updated

6.70 score 4 stars 14 scripts 249 downloads

syrona - Stratified Prevalence Comparison Across OMOP CDM Datasets

Derives stratified prevalence tables from the condition, procedure, and drug records in OMOP CDM (Observational Medical Outcomes Partnership Common Data Model) databases, computes log2 prevalence ratios between paired datasets, and synthesizes them via random-effects meta-analysis at multiple aggregation levels (year, age group, and sex). Between-study variance is estimated with the Paule-Mandel method, as described in Paule and Mandel (1982) <doi:10.6028/jres.087.022>.

Last updated

5.00 score 158 downloads